Harry Gilson: Why is Sugar Bad for You?

#3 - Published on December 8, 2025 - 6 min read

Sugar and I have (up to this point) had a strange relationship. Having gone from over-consumer to non-consumer – I know first-hand the benefits of a sugarless existence. My aim with this article is to gain an understanding of why exactly that's the case. With that said, here are the main reasons sugar is bad for you.

Develops Excess Fat

Sugar is notoriously low in nutrients like fibre, protein, and fat. Yet remarkably high in calories. Due to this fact, sugar (in it's pure form) bypasses satiety mechanisms, meaning you eat way past what you actually need until your brain says stop. Making sugar one of the main culprits when it comes to excess fat development.

Spikes Blood Sugar

Excessive consumption of sugar leads to rapid spikes in blood glucose levels, which prompts the pancreas to release insulin. Insulin is released by the pancreas when blood sugar rises. It tells cells (mainly muscle, fat, and liver) to absorb glucose from the blood, lowering blood sugar levels and providing energy or storage.

Heart Disease

High sugar intake is linked to increased risk of heart disease through multiple mechanisms. Excess sugar consumption can lead to obesity, inflammation, high triglyceride levels, and elevated blood pressure – all of which are risk factors for cardiovascular disease. Studies show that people who consume more than 25% of their daily calories from added sugars have nearly triple the risk of dying from heart disease compared to those who consume less than 10%.

Accelerates Aging

Sugar accelerates the aging process through a biochemical reaction called glycation. When sugar molecules bind to proteins and fats in your body, they form harmful compounds called Advanced Glycation End Products (AGEs). These AGEs damage collagen and elastin – the proteins that keep your skin firm and elastic. The result? Wrinkles, sagging skin, and a loss of that youthful glow. Beyond appearance, AGEs also contribute to cellular aging throughout the body, affecting organs and increasing inflammation.

Damages Teeth

Your mouth is home to bacteria that feed on sugar. When you consume sugary foods or drinks, these bacteria produce acid as a byproduct. This acid attacks tooth enamel, the hard protective outer layer of your teeth, leading to cavities and decay. Unlike other parts of your body, tooth enamel cannot regenerate once damaged. Frequent sugar consumption creates a constant acidic environment in your mouth, giving bacteria an endless feast and your teeth a relentless assault.

Increases Risk of Type 2 Diabetes

Prolonged high sugar intake forces your pancreas to constantly produce insulin. Over time, your cells become resistant to insulin's signals – a condition known as insulin resistance. When this happens, glucose remains in your bloodstream instead of entering cells, leading to chronically elevated blood sugar levels. Eventually, your pancreas can't keep up with the demand, and Type 2 diabetes develops. Excess body fat from sugar consumption, particularly around the abdomen, further compounds this risk by promoting inflammation and insulin resistance.

Impairs Cognitive Function

The brain runs on glucose, but too much sugar can actually impair cognitive function. High sugar consumption has been linked to memory problems, reduced brain plasticity, and even increased risk of dementia. Sugar causes inflammation and oxidative stress in the brain, damages blood vessels, and interferes with the production of brain-derived neurotrophic factor (BDNF), a protein essential for learning and memory. Studies have also shown that high-sugar diets can shrink the hippocampus, the brain region responsible for memory formation.

Weakens the Immune System

Sugar temporarily suppresses your immune system's ability to fight off bacteria and viruses. Research shows that consuming 100 grams of sugar (about the amount in two cans of soda) can significantly reduce the ability of white blood cells to destroy harmful pathogens for up to five hours after consumption. This immune suppression makes you more susceptible to infections and illnesses. Chronic high sugar intake also promotes inflammation throughout the body, putting your immune system in a constant state of alert and exhausting its resources.

Disrupts Gut Health

Your gut microbiome – the trillions of bacteria living in your digestive system – plays a crucial role in overall health. Sugar feeds harmful bacteria and yeast like Candida, allowing them to overgrow and crowd out beneficial bacteria. This imbalance, called dysbiosis, can lead to digestive issues, weakened immunity, mood disorders, and even increased sugar cravings (as harmful bacteria send signals to your brain demanding more of their favorite food). A healthy gut requires fiber and diverse nutrients, not simple sugars.

Contributes to Fatty Liver Disease

When you consume excess sugar, particularly fructose (found in table sugar and high-fructose corn syrup), your liver converts it to fat. Unlike glucose, which can be used by cells throughout your body, fructose is processed almost exclusively by the liver. Consuming too much forces your liver to turn that fructose into fat, which gets stored in liver cells. Over time, this leads to non-alcoholic fatty liver disease (NAFLD), which can progress to inflammation, scarring, and even liver failure. Shockingly, you can develop fatty liver disease without ever drinking alcohol – sugar alone can do the damage.

Creates Addiction-Like Dependence

Sugar activates the same reward pathways in the brain as addictive drugs. When you eat sugar, your brain releases dopamine, the "feel-good" neurotransmitter. Over time, your brain adapts by reducing dopamine receptors, meaning you need more sugar to get the same pleasurable effect. This creates a cycle of cravings and consumption that's remarkably similar to substance addiction. Withdrawal symptoms like irritability, headaches, and intense cravings are common when trying to quit sugar, making it one of the hardest dietary habits to break.

Conclusion

The evidence is overwhelming: excessive sugar consumption wreaks havoc on nearly every system in your body. From accelerated aging and cognitive decline to diabetes and heart disease, sugar's negative effects are far-reaching and well-documented. While our bodies can handle small amounts of natural sugars found in whole foods like fruit, the processed sugars hidden in so many modern foods create a toxic burden our biology wasn't designed to handle. Cutting back on sugar isn't about deprivation – it's about reclaiming your health, energy, and longevity. Your future self will thank you.